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  • Evidence is increasing that addiction without exception is related to issues with the brain's reward center, especially the mesolimbic system. This section of the problem regulates reward responses in getting food and sex, as well as in nurturing infants and children. One of the most important neurotransmitters involved in reward responses, both when they malfunction and after they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates "the level of dopamine released in in reply to a stimulus"(Bostwick & Bucci, 2008).

    Using two separate drugs to shed weight can be very effective you can find combinations while watching FDA now awaiting approval. When dealing with weight-loss and the people that go through it you should err assisting caution and allow FDA do its job and demand some research be done in order that the public understands the side effects and hazards of the medications before we bring them. Keep in mind that drug companies will be in business to make money and that they would say almost anything to keep people on the medications.

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    Seizures really are a side effect with Contrave and mustn't be taken in individuals with seizure disorders. The drug may also raise blood pressure and heartrate, and shouldn't be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure level and heartbeat and must not used in patients with uncontrolled high blood pressure levels, as well as by you are not heart-related and cerebrovascular (circulatory dysfunction impacting the mind) disease. Patients having a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients for the increased chance of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking.

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