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  • On September 26, UCLA researcher reported the outcome of a study, which indicated that Asians that are struggling with alcoholism will benefit especially from naltrexone, one of three medications approved by the U.S. Food and Drug Administration (FDA) for the treatment of alcoholism. Recent research has found that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent use a particular mutation which makes them prone to benefit from naltrexone, weighed against about 20% of Caucasians and fewer than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director in the UCLA Addictions Laboratory. The findings are presently available online ( within the journal Neuropsychopharmacology and will be published within an upcoming print edition from the journal.

    Using two separate drugs to lose weight naturally can be very effective there are combinations as you're watching FDA now awaiting approval. When dealing with weight loss and the people that go through it you need to err assisting caution and allow the FDA do its job and demand some investigation be done so that the public understands the side effects and risks of the medications before we take them. Keep in mind that drug companies come in business to generate income and that they would say almost anything to keep people on their own medications.

    Researchers found that participants using this drug for any year, lost weight within a month and have kept the body weight off through the entire 56 weeks from the study. Contrave can be a combination of the drugs naltrexone and bupropion, which generally seems to reflect a new trend of weight-loss drugs that are made up of many active ingredient, which can make them more effective and safer.

    Combo-pilling may be the newest fad or in addition to this the newest into the future under scrutiny and so it is just more publicly known although in the past, comb-pilling to lose weight has been around since the eighties. The biggest reason that by using a combination of pills has become popular is the fact that at the time of right now there aren't any long term prescription slimming capsules that have been approved by the FDA other than orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be licensed by the FDA.

    Seizures are a side effect with Contrave and mustn't be taken in those with seizure disorders. The drug could also raise hypertension and heartbeat, and mustn't be used in those with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise blood pressure level and heartbeat and must not used in patients with uncontrolled high blood pressure, as well as by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting mental performance) disease. Patients which has a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients towards the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for quitting smoking.

    The most common effects reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.